Obese mice are losing weight without breaking a sweat

Bye-bye gym membership and counting calories, hello losing pounds. Scientists at the University of Florida have found a new drug that helped obese mice lose weight while skipping their workout routine.

The wizardry lies in persuading the skeletal muscles to mimic the effects of high endurance training.

Behold the miraculous SLU-PP-332, a new substance that seemed to have induced weight loss in obese mice. Without engaging in any physical exercise, the drug somehow tricked their bodies to enter an active state. The wizardry lies in persuading the skeletal muscles to mimic the effects of high endurance training, resulting in an accelerated metabolism and enhanced endurance. It specifically targets EFF proteins, which activate energy-demanding tissues like the brain, heart, and other muscles.

Without engaging in any physical exercise, the drug somehow tricked their bodies to enter an active state.

While ERRs are naturally released during exercise, they have remained challenging to stimulate with drugs until now. However, let's not get carried away just yet. Alas, human metabolism remains an uncharted territory for SLU-PP-332, and past wand-waving attempts at similar remedies have left much to be desired. So, before bidding farewell to your gym membership, exercise caution instead: the treadmill might still have the last laugh.